Toolkit underway at WashU may give researchers insight into cancer

By studying the effects of a biochemical process on protein function, Kristen Naegle, a biomedical engineer at Washington University in St. Louis, hopes to identify new therapeutic interventions for cancer.

Kristen Naegle, assistant professor of biomedical engineering in the School of Engineering & Applied Science, has received a three-year, $610,000 grant from the National Institutes of Health’s National Cancer Institute to create a toolkit that will allow biomedical engineers to study the effects of tyrosine phosphorylation, which becomes dysregulated in cancer. The toolkit would be a fast, inexpensive and accessible way for researchers to produce phosphorylated and soluble proteins compared to current methods.

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