Technology Catalog

Search all available Washington University technologies here:

Diagnostics

Targeted Quantification of Sphingolipids for Detection of Gastrointestinal Inflammatory Disorders A Single-Platform Custom Capture Array for Detection of Multiple Myeloma Variants Novel Set of Biomarkers for Detect Multiple Myeloma Cells ViroCap Tumor Detection by Targeting and Monitoring Integrin Expression Using Synergistic Effects of Molecular Beacons and Peptides Enterovirus D68 real-time PCR
Copper Nanocolloids: Contrast Agents for Magnetic Resonance, Optical and Microwave Based ImagingUrine Biomarkers for Endoplasmic Reticulum Stress-Related Kidney DiseasesNeurofibromin/dopamine signaling as a biomarker for cognitive and behavioral problems in children with neurofibromatosis type 1 (NF1)Direct Waveform Recording-Based, Multi-Photon Fluorescence Lifetime Imaging MicroscopyC-type Atrial Natriuretic Fragment (CANF)-Cypate; an Optical Imaging AgentRespiratory Motion Compensation in Photoacoustic Computed TomographyReflector Augmentation of Detection View in Photoacoustic Computed TomographyPhotoacoustic Tomography of Human BrainGrueneisen-Memory Photoacoustic MicroscopyNonradiative Voltage-Sensitive Dye for Imaging Neuronal Action PotentialNovel Acute Myocardial Injury Biomarker ProfileNeuroactive Enantiomeric 15-, 16-, and 17-Substituted Androgens with Optimal Subsituents at Carbons 4, 7 and 19, Prodrugs Thereof, and Methods of TreatmentImmunohistochemical Diagnosis of Human Renal Chromophobe CarcinomaNoise Exposure Card SortCell Permaeable Nanoconjugates of Shell-Crosslinked Knedel (SCK) and Peptide Nucleic Acids (PNA)Polyclonal Antibody for Straining Human Cytokeratin 13Measurement of NT-ProBNP in Human Blood using a Monoclonal AntibodyMethod for Detecting Conditions Indicative of SepsisFetal Cell AntibodiesNovel Bile Acids as Biomarkers for Niemann-Pick Type C DiseaseA MicroRNA Expression Signature for the Prognosis of Oropharyngeal Squamous Cell Carcinoma24(S)-HC as a Biomarker to Monitor CNS Efficacy of 2-Hydroxypropyl-Beta-Cyclodextrin (HPBCD)Compressed-Sensing Ultrafast Photography (CUP)Diagnostic Test to Distinguish between Inflammation in the Eye & Eye CancerNew Diagnostic Test Method for Infectious DiseasesNovel Heterocyclic Molecules for Biomedical Imaging and Therapeutic ApplicationsMultifunctional Chemical Agents for metal chelation, positron emission tomography (PET) imaging, fluorescence imaging, and amyloid plaque clearance in Alzheimer’s diseaseCopy Number Aberration Driven Endocrine Response (CADER) Gene SignatureDiscovery of Plasma Lipid Biomarkers for Early Diagnosis of Alzheimer’s DiseaseGene-expression Signature Predictor for Stage I Non-Small Cell Lung CancerLow Error Amplicon Sequencing (LEA-Seq)SPECT Imaging Nanoprobe for the Detection of Matrix Metalloproteinase (MMP) ActivityCancer Imaging and Therapy by Cerenkov RadiationThromboScintBiochemical Diagnosis of Sleep DeprivationBiomarkers for the Diagnosis of Human Kidney InjuryDecision Support System for Cerebral AneurysmKnowPain Mobile Pain SensorPegylated Benzamide Analogs as Sigma-2 Selective LigandsPET Radiotracers for Imaging Free Radicals and Reactive Oxygen Species (Materials: WC-4-77)[18F] 1-(2-Fluoroethyl)-2-Aza-histidine as a Tumor Imaging AgentConformationally-flexible benzamide analogs as sigma-2 selective ligandsUrinary Biomarker of Uropathogen ColonizationSmall Molecule Inhibitor of Yersiniabactin BiosynthesisDiagnosis and Monitoring of Parkinson’s Disease Using Novel Molecules in PET ImagingFluorogenic Modified Recombinant Polypeptide Substrate to Assay the Metalloprotease ADAMTS13Gallium Based PET and SPECT Agent for Imaging of Heart DiseaseMethod and System for Quantification of Anisotropic Diffusion of Magnetic ResonanceCompounds and Methods for Optical Imaging of Myeloperoxidase Activity In VivoTwo Novel Biomarkers for Early Diagnosis of Renal Cell CarcinomaGenetic Variation in Cholinergic Nicotinic Receptor Genes is Associated with Increased Risk for Substance DependenceBiomarker for Alzheimer’s DiseaseHighly Efficient Paper Based Surface Enhanced Raman Scattering (SERS) SubstrateMethod for the Measurement of Myocardial Oxygenation with 17O-CMRQuantify Multi-tensor for Improved CNS Injury Diagnosis Using Diffusion Basis Spectrum Imaging (DBSI)Left Ventricular Pressure Recovery Ratio: An Invasive Index of Diastolic Relaxation/ViscoelasticityAdvanced Analysis of Heart Function Using Ultrasound

Medical Devices

Gaussian Process Audiogram Enhanced System for Normothermic Extracorporeal Liver Perfusion Transcranial Photoacoustic/Thermoacoustic Tomography Brain Imaging informed by Adjunct Image Data Cuffing-Based Photoacoustic Flowmetry in Humans in the Optical Diffusive Regime Reversibly Switchable Photoacoustic Tomography using a Bacterial Phytochrome as a Genetically-Encoded Near-Infrared Photochromic Probe Automated Apparatus to Improve Image Quality in X-ray
Parity-Time Symmetric Whispering-Gallery-Mode Microcavities SensorSuperpixel Detection for Wearable Diffuse Optical TomographyDevice for Treatment of Cancers at the Vaginal ApexHigh Resolution Imaging using Sub-Wavelength Grating StructuresThe Revolution Reservoir and a Non-Clogging Shunt Catheter TipMulti-Modal Surface Coil for Combined MRI-PET ScannersPlasmonic Biosensors with Built-In Artificial AntibodiesCollagen Matrix Possessing Locally Controllable Internal and Surface Mineral ContentOptical Resolution Photoacoustic Imaging Device for Port-Wine StainsPhoton TunnelingMulti-Focus Optical-Resolution Photoacoustic Microscopy with Ultrasonic Array DetectionSection-Illumination Photoacoustic Microscopy with Ultrasound Array DetectionNanofiber Scaffolds for Delivery of Heparin Binding Growth FactorsMethod and Apparatus for Optical Time Reversal by Ultrasonic Encoding in Biological TissueScanning Apparatus for Reflection-Mode Photoacoustic TomographyPhotoacoustic & Thermoacoustic Tomography for Breast Imagingy-Secretase Inhibitors as Bone Anabolic ReagentsAttenuating Influenza Virus to Produce a Live VaccineAsymmetrically-Charged NIR Fluorophores for Labeling Antibodies, Proteins and Nanoparticles with High BrightnessHands-Free Wireless Goggles for Near-Infrared Fluorescence and Real-Time Image-Guided SurgeryObjective-Coupled Selective Plane Illumination MicroscopyImage-Guided, Electrophysiologically-Determined Treatment of Atrial FibrillationKnowPain Mobile Pain SensorGallium Based PET and SPECT Agent for Imaging of Heart DiseaseMethod and System for Quantification of Anisotropic Diffusion of Magnetic ResonanceMedical Autosegmentation Method and InterfacePlanar Storage Phosphor Dosimeter for Radiation Therapy Dosimetry

Research Tools

Novel Murine Astroviruses Coupled Visualization and Ablation of Specific Cells and Tissues in Zebrafish VISIT-TS Version 2 TensR Agonistic Anti-CD40 Monoclonal Antibodies Neonatal Eating Outcome (NEO) Assessment
Monoclonal Antibodies Against Zika VirusB3 Integrin Conditional MouseJAK1-Null MiceGenetic Association of Candidate Genes with Nicotine DependenceMethod of Generating Microscopic Patterns for Protein and other MacromoleculesDetecting and Measuring Single Nanoparticles & Molecules with a Tapered Optical Fiber CIPSingle Nanoparticle Detection by Mode Splitting in Active Microresonators using Heterodyne TechniqueDirect Optical Estimation of Deformation Gradient Tensors and Crack PropagationProtease-deficient EatA Autotransporter as a Protective Antigen for Enterotoxigenic E. coliNovel Murine AstrovirusesRefractory Mo-100 Compounds as Accelerator Targets for Production of 99mTcHearing Environments and Reflection on Quality of Life (HEAR-QL) Questionnaire for Adolescents (13-18)Plasma Oxysterols as Biomarkers for Niemann-Pick C DiseaseHearing Environments and Reflection on Quality of Life (HEAR-QL) Assessment for ChildrenNew Method to Produce a DNA Mutation LibraryPegylated Benzamide Analogs as Sigma-2 Selective LigandsPET Radiotracers for Imaging Free Radicals and Reactive Oxygen Species (Materials: WC-4-77)[18F] 1-(2-Fluoroethyl)-2-Aza-histidine as a Tumor Imaging AgentConformationally-flexible benzamide analogs as sigma-2 selective ligandsSingle Chain Trimer Engagement of T Cell Receptor Induces Quicker and Greater CD8 Amplification than Current MethodsVarScanOptical Coherence Computed TomographyRotational Seismometer for Near-field Seismic and Engineering ApplicationsDementia Screening Test: AD8

Therapeutics

Chemoenzymatic Synthesis of B-lactones and B-hydroxy acids Obligate Heterotetrameric Pairs of Cre Recombinase Mutants for Efficient Recombination at Asymmetric Sites Manipulating Tricellular Junction Permeability in Blood Brain Barrier to Treat Brain Tumors Novel Anti-Arrhythmic Therapeutics Targeting Iks Channels Treatment of Human Cytomegalovirus (HCMV) with Bromodomain Inhibitors Combination of Isoform Targeted Histone Deacetylase Inhibitors and Analogs of Protein Kinase C Modulators for HIV Latency Reversal
New Technology Improves Adoptive Cellular ImmunotherapySystem and Method for Multi-modality Quantification of Neuroinflammation in Alzheimer ’s DiseaseLysosomal Enzyme GlcNAc-1-phosphotransferase with Enhanced Ability to Phosphorylate Lysosomal EnzymesRecombinantly Expressed Babesia, Theileria, Cytauxzoon, and Plasmodium CelTOS Antigen and Methods of Use ThereofControl of Dietary and Microbial Exposure in Early Life as a Novel Approach to Target Allergy Development in InfantsBiologic PacemakerNew Therapeutic for Prevention and Treatment of OsteoarthritisItaconate Immunomodulatory Properties-Ischemia ReperfusionNano-CaCO3Compositions for targeting pathologic cells and tissuesErythroMer Blood SubstituteSingle chain RANK ligand as an inhibitor of bone resorptionProtease Inhibitors of Growth Factor Activation; Serine Protease Inhibitors of Kinase SignalingPEGylated-GIRLRG Peptide for Radiopharmaceutical DeliveryBother from Allergic and Dermatologic Symptoms/Side Effects of TreatmentAnti 14-3-3 Epsilon Monoclonal AntibodyNeuroactive 19-Alkoxy-Substituted Steroids, Prodrugs Thereof, and Methods of Treatment Using SameTAKE 3: Revolutionizing Cancer Therapy with New Generation TR3 Biologics18-Substituted Steroids and Related Tetracyclic & Tricyclic Analogues with Neuronal ActionsEnantiomeric16-ketosteroids and Related Tetracyclic & Tricyclic Analogues with Neuronal ActionsNovel Steroid Anesthetic AgentsGraft-vs-Host Disease Prevention during Stem Cell TransplantationBiomarkers for Human Kidney InjuryAcyl-CoA-Mediated Reversal of Calmodulin Inhibition of Calium-Independent Phospholipase A2Beta (iPLA2Beta) ActivityMonitoring and Managing Glycemia Status in Diabetic PatientsSPRR3 Protein as a Marker of Vascular AtherosclerosisBiomarkers for Human Brain InjuryModulation of Lymphocyte ActivityPhospholipase A2 EpsilonNeuroactive 13, 24-Cyclo-18, 21-Dinorcholanes and Structurally-Related Pentacyclic SteroidsCalcium-Independent Phospholipase A2 induces Ischemic Ventricular TachyarrhythmiasFES Recovery of Neurologic Function and RegenerationSelective Inhibition of iPLA2Beta and iPLA2Gamma by S- & R-BELHydrogels for Localized RadiotherapyPorcine Knob Xenotype Chimeric Adenoviral Vector for Dendritic Cell InfectionCombination Artemisinin and Chemiluminescent Photodynamic Therapy for Treatment of Malaria and CancerStyryl Heteroaromatic Ring Containing Analogues for Alpha-SynucleinSmall Molecule Inhibition of Discoidin Domain Receptor 2Discovery of Importance of Bromodomain Proteins in Human Cytomegalovirus InfectionInhibition of Choroidal Neovascularization (CNV) in Age-Related Macular Degeneration by Upregulation of Cholestrol Efflux Pathways in MacrophagesCompounds Containing 4-Benzoylpiperidine as Highly Selective Sigma-1 Receptor LigandsSmall Molecule Inhibitors of Taspase1Anti-mucus drug, WU compound 89Red-Shifted Chromophore Substitution for Optogenetic ApplicationsVaccines for the Pathogenic Fungus Cryptococcus Neoformans via Nasal InoculationRational Design of MicroRNA-siRNA Chimeras for Multi-functional Target SuppressionIntraocular Artificial LensesFluorogenic Modified Recombinant Polypeptide Substrate to Assay the Metalloprotease ADAMTS13Non-Hormone Based Intra-Uterine ContraceptivesEndogenous Ligand for PPAR-Alpha in LiverSingle Chain Trimer Engagement of T Cell Receptor Induces Quicker and Greater CD8 Amplification than Current MethodsAlzheimer’s Disease Plaques Targeted by Blood-brain Barrier Permeant PeptideNovel Therapy for Neuromuscular DiseasesMOR1D Mediates Opioid and Liver Disease-Induced Itch via GRPRPro-drug Nanoparticle TechnologyTreatment for Centrally Mediated ItchingPhage Antibodies to Radiation-Inducible NeoantigensIn Vivo Panning for Ligands to Radiation-Induced MoleculesX-ray Guided Drug DeliverySynergistic Drug Therapy to Ameliorate Hearing LossModulation of the DLK/JNK Pathway as a Method for Inhibiting Axonal DegenerationNew Vasodilatory Shock TreatmentIntranasal Administration of Leptin to Treat SeizuresInduction of Cell Death by the Type Collagen Amino PropeptideRadiopharmaceutical Diagnosis of Cerebral Amyloid Angiopathy